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Bladder Squamous Cell Carcinoma¹

¹ From the Department of Radiology, University of Minnesota, Minnesota Veterans Administration Medical Center, Minneapolis, Minn. Received June 24, 2003; revision requested July 23 and received September 5; accepted September 5. Address correspondence to J.T.W., Department of Radiology, University of Minnesota, 420 Delaware St SE, Minneapolis, MN 55455 (e-mail: wongx036@umn.edu).

View larger version (137K): [in a new window]   Figure 1a.  Contrast material-enhanced CT cystograms demonstrate a lobulated soft-tissue filling defect. Anterior extension into the prevesical fat is suggested in a (arrow). In b, the mass is seen to extend superiorly along the right superior lateral wall from the point of suprapubic catheter insertion.

View larger version (136K): [in a new window]   Figure 1b.  Contrast material-enhanced CT cystograms demonstrate a lobulated soft-tissue filling defect. Anterior extension into the prevesical fat is suggested in a (arrow). In b, the mass is seen to extend superiorly along the right superior lateral wall from the point of suprapubic catheter insertion.

View larger version (107K): [in a new window]   Figure 2.  Photograph of the bladder (opened anteriorly with the prostate gland placed to the left) demonstrates a white friable mass that corresponds to the filling defect seen at CT cystography. A separate partial segment of urethra over a section of red rubber tubing (arrow) was submitted for pathologic analysis.

View larger version (110K): [in a new window]   Figure 3.  Photograph of the cross-sectioned lesion suggests tumor extension through the muscular layers into the prevesical fat (arrow).

View larger version (177K): [in a new window]   Figure 4.  Low-power photomicrograph (original magnification, x40; hematoxylin-eosin stain) demonstrates extension of squamous cell carcinoma into the prevesical fat (arrows). Note the keratinized islands (squamous pearls) composed of concentric cell aggregations (arrowheads).