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Residents' Teaching Files1

Mucinous Cystic Neoplasm of the Pancreas

Jose E. de Lima, Jr, MD, Marcia C. Javitt, MD and Sharad C. Mathur, MD

1 From the Departments of Radiology (J.E.d.L., M.C.J.) and Pathology (S.C.M.), The George Washington University Medical Center, 901 23rd St NW, Washington, DC 20037. Received November 20, 1998; revision requested January 4, 1999, and received February 3; accepted February 4. Address reprint requests to J.E.d.L.



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Figure 1. Figures 1, 2. (1) CT scan shows a large cystic mass with evident septation in the left upper quadrant that displaces bowel loops. The mass is well circumscribed, and no signs of adjacent organ invasion can be seen. (2) CT scan of an upper portion of the mass shows its relationship to the remainder of the pancreas. Gross calcifications are noted within the cyst wall. Again, the cystic nature of the mass and the septations are clearly seen.

 


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Figure 2. Figures 1, 2. (1) CT scan shows a large cystic mass with evident septation in the left upper quadrant that displaces bowel loops. The mass is well circumscribed, and no signs of adjacent organ invasion can be seen. (2) CT scan of an upper portion of the mass shows its relationship to the remainder of the pancreas. Gross calcifications are noted within the cyst wall. Again, the cystic nature of the mass and the septations are clearly seen.

 


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Figure 3.  Photograph of the mass during surgical resection shows its large size and smooth, well-defined margins.

 


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Figure 4a.  (a) Photomicrograph (original magnification, x25; hematoxylin-eosin stain) of the cyst wall shows mucinous epithelium overlying dense stroma and fibrous tissue. (b) Photomicrograph (original magnification, x50; hematoxylin-eosin stain) shows a micropapillary epithelial pattern with mild atypia and nuclear crowding.

 


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Figure 4b.  (a) Photomicrograph (original magnification, x25; hematoxylin-eosin stain) of the cyst wall shows mucinous epithelium overlying dense stroma and fibrous tissue. (b) Photomicrograph (original magnification, x50; hematoxylin-eosin stain) shows a micropapillary epithelial pattern with mild atypia and nuclear crowding.

 





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