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DOI: 10.1148/rg.265065001
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RadioGraphics 2006;26:1305-1333
© RSNA, 2006


EDUCATION EXHIBIT

VIRTOPSY: Minimally Invasive, Imaging-guided Virtual Autopsy

Richard Dirnhofer, MD, Christian Jackowski, MD, Peter Vock, MD, Kimberlee Potter, PhD and Michael J. Thali, MD

1 From the Institute of Forensic Medicine, University of Bern, Buehlstrasse 20, CH-3012 Bern, Switzerland (R.D., C.J., M.J.T.); the Institute of Diagnostic Radiology, Inselspital, University of Bern, Bern, Switzerland (P.V.); and the Armed Forces Institute of Pathology, MRM Facility, Washington, DC (K.P.). Presented as an education exhibit at the 2003 RSNA Annual Meeting. Received January 3, 2006; revision requested January 30 and received March 23; accepted March 24. All authors have no financial relationships to disclose. Address correspondence to M.J.T. (e-mail: michael.thali{at}irm.unibe.ch).

Invasive "body-opening" autopsy represents the traditional means of postmortem investigation in humans. However, modern cross-sectional imaging techniques can supplement and may even partially replace traditional autopsy. Computed tomography (CT) is the imaging modality of choice for two- and three-dimensional documentation and analysis of autopsy findings including fracture systems, pathologic gas collections (eg, air embolism, subcutaneous emphysema after trauma, hyperbaric trauma, decomposition effects), and gross tissue injury. Various postprocessing techniques can provide strong forensic evidence for use in legal proceedings. Magnetic resonance (MR) imaging has had a greater impact in demonstrating soft-tissue injury, organ trauma, and nontraumatic conditions. However, the differences in morphologic features and signal intensity characteristics seen at antemortem versus postmortem MR imaging have not yet been studied systematically. The documentation and analysis of postmortem findings with CT and MR imaging and postprocessing techniques ("virtopsy") is investigator independent, objective, and noninvasive and will lead to qualitative improvements in forensic pathologic investigation. Future applications of this approach include the assessment of morbidity and mortality in the general population and, perhaps, routine screening of bodies prior to burial.

© RSNA, 2006




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